Alkaloid (818D) isolated from Vinca (periwinkle) : binds to tubulin heterodimer and induces formation of paracrystals rather than tubules. Net result is that microtubules disappear as they disassemble and are not replaced. Used in tumour chemotherapy.

Dictionary of molecular biology. 2004.

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  • Vinblastine — Systematic (IUPAC) name dimethyl (2β,3β,4β,5α,12β,19α) 15 [(5S,9S) 5 ethyl 5 hydroxy 9 (methoxycarbonyl) Clinical data AHFS/ …   Wikipedia

  • Vinblastine — Général No CAS …   Wikipédia en Français

  • vinblastine — [vin blas′tēn, vin blas′tin] n. an alkaloid, C46H58N4O9·H2SO4, obtained from the leaves of a periwinkle ( Vinca rosea) and used as a drug in the treatment of Hodgkin s disease and other lymphomas: in full vinblastine sulfate …   English World dictionary

  • vinblastine — vinblastine. См. винбластин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • vinblastine — ● vinblastine nom féminin Alcaloïde indolique extrait de la pervenche rose (Vinca rosea), utilisé pour son action antimitotique, en particulier dans le traitement de la maladie de Hodgkin …   Encyclopédie Universelle

  • vinblastine — noun Etymology: contraction of vincaleukoblastine, from vinca + leukoblast developing leukocyte, from leuk + blast Date: 1962 an alkaloid C46H58N4O9 from the rosy periwinkle used especially in the form of its sulfate to treat human neoplastic… …   New Collegiate Dictionary

  • vinblastine — /vin blas teen/, n. Pharm. an alkaloid, C46H58N4O9, derived from the periwinkle Vinca rosea, used in the treatment of various malignant conditions, esp. in the management of lymphomas. [1960 65; < NL Vin(ca) a periwinkle genus + (LEUKO)BLAST +… …   Universalium

  • vinblastine — noun A particular drug used in chemotherapy …   Wiktionary

  • vinblastine — vin·blas·tine ( )vin blas .tēn n an alkaloid that is obtained from the rosy periwinkle and that is used esp. in the form of its sulfate C46H58N4O9·H2SO4 to treat human neoplastic diseases (as Hodgkin s disease and testicular carcinoma) called… …   Medical dictionary

  • vinblastine — vin·blas·tine …   English syllables

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